› Dissecting ribosome and translation initiation factor binding using high throughput approaches reveals novel regulatory elements in 5′-UTRs - Ritam Neupane
09:00-09:20 (20min)
› GTP hydrolysis by eIF2 and binding of eIF5B rearrange the human 48S initiation complex for 60S subunit joining - Niels Fischer
09:20-09:40 (20min)
› Structure of a human 48S reveals how eIF4F and eIF4A regulate translation initiation - Jailson Brito Querido
09:40-10:00 (20min)
› The structural dynamics of mRNA recruitment during eukaryotic translation initiation - Riley Gentry
10:00-10:20 (20min)
› Compact IF2 gates the ribosome to elongation - Matthieu Gagnon
10:20-10:40 (20min)
› Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding - Karissa Sanbonmatsu
11:20-11:40 (20min)
› Structural insights into the decoding capability of tRNA with cytidine modifications - Naho Akiyama
11:40-12:00 (20min)
› Codon position-specific engineering of translation kinetics monitored by Live Imaging on Single Cell Arrays (LISCA) - Sophia Rudorf
12:00-12:20 (20min)
› Impact of ribosomes, mRNA sequence and nascent protein chain on efficiency and accuracy of protein synthesis - Sergej Djuranovic
12:20-12:40 (20min)
› Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation - Dmitri Ermolenko
14:00-14:20 (20min)
› Insights into the ribosome function from the structures of non-arrested ribosome nascent chain complexes. - Yury Polikanov
14:20-14:40 (20min)
› Variable sequences in the Archaeal A loop stabilize the bacterial ribosome - Amos Nissley
14:40-15:00 (20min)
› Revealing transient processes governing translation through the integration of single-molecule imaging and cryo-electron microscopy - Scott Blanchard
15:00-15:20 (20min)
› Alexander Spirin (1931-2020). Role of diphthamide in the ribosomal translocation. E-site specificity of Candida albicans ribosome. - Marat Yusupov
15:40-16:00 (20min)
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Main hall (Espace de la Bourse)
