› Dissecting ribosome and translation initiation factor binding using high throughput approaches reveals novel regulatory elements in 5′-UTRs - Ritam Neupane
09:00-09:20 (20min)
› GTP hydrolysis by eIF2 and binding of eIF5B rearrange the human 48S initiation complex for 60S subunit joining - Niels Fischer
09:20-09:40 (20min)
› Structure of a human 48S reveals how eIF4F and eIF4A regulate translation initiation - Jailson Brito Querido
09:40-10:00 (20min)
› The structural dynamics of mRNA recruitment during eukaryotic translation initiation - Riley Gentry
10:00-10:20 (20min)
› Compact IF2 gates the ribosome to elongation - Matthieu Gagnon
10:20-10:40 (20min)
› Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding - Karissa Sanbonmatsu
11:20-11:40 (20min)
› Structural insights into the decoding capability of tRNA with cytidine modifications - Naho Akiyama
11:40-12:00 (20min)
› Codon position-specific engineering of translation kinetics monitored by Live Imaging on Single Cell Arrays (LISCA) - Sophia Rudorf
12:00-12:20 (20min)
› Impact of ribosomes, mRNA sequence and nascent protein chain on efficiency and accuracy of protein synthesis - Sergej Djuranovic
12:20-12:40 (20min)
› Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation - Dmitri Ermolenko
14:00-14:20 (20min)
› Insights into the ribosome function from the structures of non-arrested ribosome nascent chain complexes. - Yury Polikanov
14:20-14:40 (20min)
› Variable sequences in the Archaeal A loop stabilize the bacterial ribosome - Amos Nissley
14:40-15:00 (20min)
› Revealing transient processes governing translation through the integration of single-molecule imaging and cryo-electron microscopy - Scott Blanchard
15:00-15:20 (20min)
› Alexander Spirin (1931-2020). Role of diphthamide in the ribosomal translocation. E-site specificity of Candida albicans ribosome. - Marat Yusupov
15:40-16:00 (20min)
› Effects of cryo-EM cooling on structural ensembles - Helmut Grubmueller
12:20-12:40 (20min)
› Single-molecule tracking for kinetics measurements of protein synthesis, folding, and targeting inside living cells - Mikhail Metelev
12:40-13:00 (20min)
› Ribosomal antibiotics as modulators of translation - Alexander Mankin
14:00-14:20 (20min)
› Context-dependent inhibition of bacterial protein synthesis by ribosome-targeting antibiotics - Axel Innis
14:20-14:40 (20min)
› Context-Specific Inhibition of Translation by Oxazolidinone Antibiotics - Danica Galonic Fujimori
14:40-15:00 (20min)
› Ribosome-targeting antibiotics and bacterial resistance mechanisms - Daniel Wilson
15:00-15:20 (20min)
› Cryo-EM studies of all four E. coli ABCF paralogs establish the general principles underlying reciprocal allosteric linkage of the ATPase activity of ABCF proteins to global ribosome conformation and PTC structure - Shikha Singh
15:20-15:40 (20min)
› Complementary mechanisms of ribosome inhibition by known antibiotics - Pohl Milon
15:40-16:00 (20min)
› Activation mechanism of mitochondrial translation by LRPPRC-SLIRP - Alexey Amunts
09:45-10:05 (20min)
› Human mitochondria require mtRF1 for translation termination at non-canonical stop codons - Joanna Rorbach
10:05-10:25 (20min)
› The Giardia lamblia ribosome structure at 2.49 Å reveals divergence in several biological pathways and the mode of emetine function - Jeffrey Kieft
10:25-10:45 (20min)
› Translocation Intermediates of Giardia intestinalis Ribosome Provide Insights into the Evolution of Eukaryotic Translation Machinery - Suparna Sanyal
10:45-11:05 (20min)
› eIF5A is a Sensor and Effector for Polyamine Regulation of Translation -
11:35-11:55 (20min)
› ANTIBIOTIC RESISTANCE OR SIGNALING? The role of ABCF-ATPases in antibiotic producers. -
11:55-12:15 (20min)
› The ABC-F protein EttA regulates specific protein synthesis by alleviating early ribosomal translational stalling during mRNA translation. -
12:15-12:35 (20min)
› A new paradigm in virus-host arms race: How does the host encoded ZAP-S alter conformational dynamics and translation of frameshifting RNAs? - Neva Caliskan
12:35-12:55 (20min)
› Alterations in mRNA translation initiation in colorectal cancer - Yaser Hashem
12:55-13:15 (20min)
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Main hall (Espace de la Bourse)
